White Matter Changes in HIV+ Women with a History of copyright Dependence

White Matter Changes in HIV+ Women with a History of copyright Dependence

Blog Article

copyright use is associated with the transmission of human immunodeficiency (HIV) virus through risky sexual behavior.In HIV+ individuals, copyright use is linked with poor health outcomes, including HIV-medication non-adherence and faster disease progression.Both HIV and copyright dependence are vush gloss bullet vibrator associated with reduced integrity of cerebral white matter (WM), but the effects of HIV during copyright abstinence have not yet been explored.

We used diffusion tensor imaging (DTI) to understand the effect of combined HIV+ serostatus and former copyright dependence on cerebral WM integrity.DTI data obtained from 15 HIV+ women with a history of copyright dependence (COC+/HIV+) and 21 healthy females were included in the analysis.Diffusion-based measures [fractional anisotropy (FA), radial ruoan s?ilytysastia diffusivity (RD), mean diffusivity, and axial diffusivity] were examined using tract-based spatial statistics and region-of-interest analyses.

In a whole-brain analysis, COC+/HIV+ women showed significantly reduced FA and increased RD in all major WM tracts, except the left corticospinal tract for RD.The tract with greatest percentage of voxels showing significant between-group differences was the forceps minor (FA: 75.6%, RD: 59.

7%).These widespread changes in diffusion measures indicate an extensive neuropathological effect of HIV and former copyright dependence on WM.